If you’ve been dealing with depression for a while, you’ve probably tried more than your fair share of treatments. Maybe you’ve been through different medications, therapy sessions, and lifestyle changes, hoping each time that something would finally click. But it’s exhausting when the relief you’re looking for stays just out of reach. If that sounds like your journey, there’s a newer option to consider: Spravato.
Spravato (esketamine) has emerged as a promising treatment for those who haven’t found success with traditional antidepressants. Here, we’ll explore what Spravato is, how it works, and what you can expect if you’re considering this innovative approach.
Spravato is a prescription nasal spray that contains esketamine, a derivative of ketamine. It’s been specifically approved by the FDA for treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts. Unlike conventional antidepressants, which often target serotonin, dopamine, or norepinephrine, Spravato works differently. It targets NMDA receptors in the brain, which play a role in mood regulation and synaptic plasticity. This unique mechanism of action allows it to work faster for many patients.
This means that while traditional antidepressants can take weeks or months to start working, Spravato might begin to relieve symptoms within hours or days. For those who have struggled with long waiting periods and the frustration of trial-and-error treatment, Spravato offers a glimmer of hope.
You deserve care that recognizes the complexity of your experience, especially if you’ve already tried multiple medications without success. Here’s why Spravato might be the right choice if you’re dealing with depression that hasn’t responded to other treatments:
If you’re considering Spravato, knowing what to expect can help make the process feel less intimidating. Here’s a breakdown of what the treatment looks like:
Initial Consultation: We’ll start with an in-depth discussion to see if Spravato is right for you. This is a chance to talk about your history with depression, previous treatments, and any other factors that could influence your care plan. Our focus is on truly hearing you—no rushing, no assumptions.
Administration in a Controlled Setting: Spravato is administered as a nasal spray in our office, where we guide you through the process step-by-step. After each dose, you’ll stay in our care for about two hours so that we can monitor you for any side effects or changes in mood.
Regular Treatment Sessions: Spravato is typically administered twice a week for the first four weeks, and then less frequently as you progress. During each session, we’ll be right there with you, providing a safe space to process any effects and ensuring your comfort.
Continuous Support: We don’t believe in “set it and forget it” care. As you go through Spravato treatment, we’ll be checking in regularly, adjusting your treatment plan as needed, and offering support that adapts to your changing needs.
As with any treatment, it’s important to understand the potential side effects of Spravato. Some people may temporarily experience dizziness, dissociation, or increased blood pressure after administration. These effects typically subside within the two-hour observation period, but we’ll always be there to help you manage them. Transparency and trust are at the core of our practice, so we’ll walk you through every aspect of what to expect before you begin.
Choosing a new treatment can be overwhelming, especially when you’ve been let down before. If you’re feeling stuck, we’re here to help you explore whether Spravato is a good fit for your unique situation. We know how disheartening it is to feel like just another number in the system, which is why we prioritize a personalized approach.
Whether you’ve felt unheard or your depression hasn’t responded to other treatments, you deserve to find an option that makes a difference. And if Spravato is the right step for you, we’re here to make sure your journey feels safe, supported, and genuinely centered on your well-being.
If you’re tired of the status quo and looking for a new path forward, reach out to us. Our team understands the challenges you’ve faced because we’ve been there, too. We’re committed to offering innovative solutions like Spravato that recognize the complexity of your experience and give you the care you deserve.
Let’s find a treatment plan that’s as unique as you are and start building a brighter future—together.